Abstract
INTRODUCTION: Minocycline is an antibiotic used for the treatment of acne. It has been associated with several autoimmune syndromes, including drug-induced lupus, autoimmune hepatitis, and vasculitis. METHOD AND RESULTS: We report a case of a 28-year-old previously healthy woman who developed a left sciatic mononeuropathy 2 weeks after starting minocycline for acne. Magnetic resonance imaging studies supported the localization. A biopsy of the left sural nerve revealed acute nerve large arteriole necrotizing vasculitis. Her condition improved after the withdrawal of minocycline and a course of treatment with methylprednisolone. CONCLUSION: This case provides further evidence that minocycline may induce a nonsystemic necrotizing vasculitis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 231-234 |
| Number of pages | 4 |
| Journal | Journal of clinical neuromuscular disease |
| Volume | 12 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jun 2011 |
Keywords
- drug-induced neuropathy
- inflammatory neuropathy
- minocycline
- peripheral neuropathy
- vasculitic neuropathy
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
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