U-curved relation between total fasting serum cholesterol and hostility: A population-based study

K. Fizazi, D. M. Prow, K. A. Do, X. Wang, L. Finn, J. Kim, D. Daliani, C. N. Papandreou, S. M. Tu, R. E. Millikan, L. C. Pagliaro, C. J. Logothetis, R. J. Amato

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Some researchers have found higher cholesterol levels linearly related to hostility, whereas others have found no relation. Even so, it remains unclear whether research should seek to find a linear relation between hostility and cholesterol levels. We hypothesized that a U-curved association was the proper test of the relation between hostility and cholesterol. Total fasting and low-density lipoprotein (LDL) cholesterol levels were collected from a population-based sample of 2,306 Canadians. Barefoot's (1989) scoring of the Cook-Medley Hostility Scale was used to assess hostility levels. Both a linear and a U-curved relation among hostility scores, fasting total, and LDL cholesterol levels were significant. Participants with low and high cholesterol levels had significantly higher hostility scores than the normal cholesterol group. A U-curved relation between hostility and serum cholesterol levels may be a more appropriate function to consider given the all-cause mortality findings we seek to explain.

Original languageEnglish (US)
Pages (from-to)282-292
Number of pages11
JournalInternational Journal of Behavioral Medicine
Issue number4
StatePublished - Jan 1 2001


  • Hostility
  • Low-density lipoprotein (LDL) cholesterol
  • Mortality
  • Serum cholesterol

ASJC Scopus subject areas

  • Applied Psychology


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