Type I interferon pathway in adult and juvenile dermatomyositis

Emily C. Baechler, Hatice Bilgic, Ann M. Reed

Research output: Contribution to journalReview articlepeer-review

71 Scopus citations


Gene expression profiling and protein studies of the type I interferon pathway have revealed important insights into the disease process in adult and juvenile dermatomyositis. The most prominent and consistent feature has been a characteristic whole blood gene signature indicating upregulation of the type I interferon pathway. Upregulation of the type I interferon protein signature has added additional markers of disease activity and insight into the pathogenesis of the disease.

Original languageEnglish (US)
Article number249
JournalArthritis Research and Therapy
Issue number6
StatePublished - Dec 22 2011

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology


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