TY - JOUR
T1 - Trisomy 9 in hematologic disorders
T2 - Possible association with primary thrombocytosis
AU - Cournoyer, Denis
AU - Noël, Pierre
AU - Schmidt, Michael A.
AU - Dewald, Gordon W.
PY - 1987/7
Y1 - 1987/7
N2 - Ten patients with a hematologic disorder and a clone of cells with trisomy 9 in the bone marrow were studied in order to investigate the clinical significance of this chromosome anomaly. In five of the patients, trisomy 9 was the only anomaly; in four, there was also trisomy 8; and in one, a Y chromosome was also lacking. Four patients had a myelodysplastic syndrome, and six had a myeloproliferative disorder. Interestingly, four patients had primary thrombocytosis.
AB - Ten patients with a hematologic disorder and a clone of cells with trisomy 9 in the bone marrow were studied in order to investigate the clinical significance of this chromosome anomaly. In five of the patients, trisomy 9 was the only anomaly; in four, there was also trisomy 8; and in one, a Y chromosome was also lacking. Four patients had a myelodysplastic syndrome, and six had a myeloproliferative disorder. Interestingly, four patients had primary thrombocytosis.
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U2 - 10.1016/0165-4608(87)90262-7
DO - 10.1016/0165-4608(87)90262-7
M3 - Article
C2 - 3472649
AN - SCOPUS:0023253682
SN - 0165-4608
VL - 27
SP - 73
EP - 78
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 1
ER -