Abstract
Although liver metastases from colorectal cancer previously conferred a very dismal prognosis, advances in systemic therapy combined with surgical techniques now gives these patients a reasonable chance for cure. Traditional cytoxic chemotherapy combined with biologic agents result in impressive response rates, allowing a portion of patients who were considered unresectable to undergo hepatectomy with curative intent. This review discusses the role of systemic therapy in patients with liver-limited metastatic disease for patients with resectable, potentially resectable and unresectable disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 235-240 |
| Number of pages | 6 |
| Journal | Cancer Journal |
| Volume | 16 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 1 2010 |
Keywords
- Adjuvant chemotherapy
- Colorectal liver metastases
- Liver neoplasms
- Neoadjuvant chemotherapy
ASJC Scopus subject areas
- Oncology
- Cancer Research