TY - JOUR
T1 - Treatment of Hypereosinophilic Syndromes with Prednisone, Hydroxyurea, and Interferon
AU - Butterfield, Joseph H.
PY - 2007/8/1
Y1 - 2007/8/1
N2 - The hypereosinophilic syndromes continue to challenge our clinical acumen and skills. Prednisone, hydroxyurea, and interferon alpha 2b are three of the oldest agents that allow control of eosinophilia and its devastating clinical consequences. They still work. As our experience with them has grown, it has become evident that use of these agents in combination will control eosinophilia in most patients. Moreover, with time, the doses can frequently be reduced. Even with the advent of newer agents for treatment of hypereosinophilic syndromes, these three medications still afford an excellent, cost-effective avenue for disease management.
AB - The hypereosinophilic syndromes continue to challenge our clinical acumen and skills. Prednisone, hydroxyurea, and interferon alpha 2b are three of the oldest agents that allow control of eosinophilia and its devastating clinical consequences. They still work. As our experience with them has grown, it has become evident that use of these agents in combination will control eosinophilia in most patients. Moreover, with time, the doses can frequently be reduced. Even with the advent of newer agents for treatment of hypereosinophilic syndromes, these three medications still afford an excellent, cost-effective avenue for disease management.
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U2 - 10.1016/j.iac.2007.06.003
DO - 10.1016/j.iac.2007.06.003
M3 - Review article
C2 - 17868861
AN - SCOPUS:34548495600
SN - 0889-8561
VL - 27
SP - 493
EP - 518
JO - Immunology and Allergy Clinics of North America
JF - Immunology and Allergy Clinics of North America
IS - 3
ER -