Transcatheter aortic valve insertion after previous mitral valve operation

Kevin L. Greason, Gurpreet S. Sandhu, Vuyisile T. Nkomo, Katherine S. King, David L. Joyce, Eric E. Williamson, David R. Holmes

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Objective There are limited data on transcatheter aortic valve insertion after previous mitral valve operation. To better understand the associated procedural risks, we reviewed our single-center experience. Methods We retrospectively reviewed the records of 772 consecutive patients who received transcatheter aortic valve insertion from November 2008 through August 2016. There were 18 (2%) patients who had previous mitral valve operation that included valve repair in 4 patients (22%) and replacement in 14 (78%). Results Baseline characteristics included age of 77 years (interquartile range 68, 84), female sex in 11 patients (61%), New York Heart Association functional class III/IV in 14 (78%), and Society of Thoracic Surgeons predicted risk of mortality of 7.0% (5.3, 12.0). Access was transfemoral in 14 patients (78%). Valve insertion was successful in all patients and involved a balloon expandable device in 10 (56%). No patient experienced acute mitral valve dysfunction or procedure-related mortality. Follow-up echocardiography demonstrated mean systolic aortic valve gradient of 9 mm Hg (8, 12), no grade moderate or greater aortic paravalvular regurgitation, and stable mitral valve function. Kaplan-Meier estimated survival was 90.9% ± 9.1% at 1 year. Conclusions Transcatheter aortic valve insertion appears to be a safe and effective operation after previous mitral valve operation. Procedure success was achieved with both balloon expandable and self-expanding devices and was independent of arterial access method. Transcatheter valve insertion should not be denied strictly on the basis of a previous mitral valve operation.

Original languageEnglish (US)
Pages (from-to)810-815
Number of pages6
JournalJournal of Thoracic and Cardiovascular Surgery
Issue number3
StatePublished - Sep 2017


  • aortic stenosis
  • complication
  • mitral valve repair
  • mitral valve replacement
  • transcatheter aortic valve insertion
  • transcatheter aortic valve replacement

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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