Tobacco treatment outcomes in patients with and without a history of depression, Czech republic, 2005-2010

Lenka Stepankova, Eva Kralikova, Kamila Zvolska, Alexandra Kmetova, Milan Blaha, Zbynek Bortlicek, Michal Sticha, Martin Anders, Darrell R. Schroeder, Ivana T. Croghan

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Introduction: Higher prevalence of smoking among depressed patients, as well as the risk of depression in smokers, is well documented. The proportion of patients with a history of depression among those seeking intensive treatment of tobacco dependence is also high. In contrast, evidence of treatment success in this subgroup of patients is controversial. The aim of this study was to compare smoking abstinence rates after tobacco treatment in smokers with and without a history of depression. Methods: We reviewed retrospective data from 1,730 smokers seeking treatment in Prague, Czech Republic. History of depression was defined as past diagnosis of depression or current treatment of depression. After a 1-year, self-reported smoking status was validated by expired-air carbon monoxide. We used logistic regression to analyze associations between abstinence rates, history of depression, and other factors (eg, age, sex, tobacco dependence). Results: Of 1,730 smokers treated, 289 (16.7%) had a history of depression. The smoking abstinence rate at 1 year was 32.5% for smokers with a history of depression and 38.7% for those with no history (P = .048). Among women, abstinence did not differ between groups (35.0% vs 35.7%; P = .86). However, among men, those with a history of depression had lower rates of abstinence (27.4% vs 41.3%; P = .009). After adjustment for baseline covariates, history of depression was not significantly associated with smoking abstinence in men or women. Conclusion: Intensive outpatient tobacco treatment programs can achieve abstinence rates among smokers with a history of depression similar to rates among the general population.

Original languageEnglish (US)
Article number130051
JournalPreventing Chronic Disease
Issue number9
StatePublished - Sep 2013

ASJC Scopus subject areas

  • Health Policy
  • Public Health, Environmental and Occupational Health


Dive into the research topics of 'Tobacco treatment outcomes in patients with and without a history of depression, Czech republic, 2005-2010'. Together they form a unique fingerprint.

Cite this