Tissue Ablation: Applications and Perspectives

Hyeongseop Keum, Enes Cevik, Jinjoo Kim, Yusuf M. Demirlenk, Dila Atar, Gia Saini, Rahul A. Sheth, Amy R. Deipolyi, Rahmi Oklu

Research output: Contribution to journalReview articlepeer-review

Abstract

Tissue ablation techniques have emerged as a critical component of modern medical practice and biomedical research, offering versatile solutions for treating various diseases and disorders. Percutaneous ablation is minimally invasive and offers numerous advantages over traditional surgery, such as shorter recovery times, reduced hospital stays, and decreased healthcare costs. Intra-procedural imaging during ablation also allows precise visualization of the treated tissue while minimizing injury to the surrounding normal tissues, reducing the risk of complications. Here, the mechanisms of tissue ablation and innovative energy delivery systems are explored, highlighting recent advancements that have reshaped the landscape of clinical practice. Current clinical challenges related to tissue ablation are also discussed, underlining unmet clinical needs for more advanced material-based approaches to improve the delivery of energy and pharmacology-based therapeutics.

Original languageEnglish (US)
Article number2310856
JournalAdvanced Materials
Volume36
Issue number32
DOIs
StatePublished - Aug 8 2024

Keywords

  • ablative therapy
  • abscopal effect
  • immunotherapy
  • locoregional therapy
  • tissue ablation
  • tumor necrosis

ASJC Scopus subject areas

  • General Materials Science
  • Mechanics of Materials
  • Mechanical Engineering

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