The year in cardiothoracic and vascular anesthesia: Selected highlights from 2011

Prakash A. Patel, Harish Ramakrishna, Michael Andritsos, Tygh Wyckoff, Hynek Riha, John G.T. Augoustides

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


There have been rapid advances in oral anticoagulation. The oral factor Xa inhibitors rivaroxaban and apixaban and the oral direct thrombin inhibitor dabigatran recently have been rigorously evaluated. These novel anticoagulants will usher in a new paradigm for perioperative anticoagulation. Perioperative blood conservation in cardiac surgery recently has been highlighted in the updated guidelines by the Society of Cardiovascular Anesthesiologists and the Society of Thoracic Surgeons. These recommendations reflect a comprehensive evaluation of the recent evidence to optimize transfusion practice. Transcatheter mitral valve repair continues to mature. Transcatheter aortic valve implantation for aortic stenosis has entered the clinical mainstream, with randomized trials showing its superiority over medical management and its equivalency to surgical valve replacement in high-risk patients. This transformational technology represents a major leadership opportunity for the cardiac anesthesiologist. Minimally invasive valve surgery has shown effectiveness in high-risk patients. Radial access is equivalent to femoral access for percutaneous coronary intervention in acute coronary syndromes but significantly reduces the risk of local vascular complications. Recent trials have further clarified the roles of medical therapy, percutaneous coronary intervention, and coronary artery bypass surgery in patients with significant coronary artery disease and left ventricular dysfunction. The past year has witnessed major advances in cardiovascular practice with new drugs, new devices, and new guidelines. The coming year most likely will advance these achievements to enhance the care of patients.

Original languageEnglish (US)
Pages (from-to)3-10
Number of pages8
JournalJournal of Cardiothoracic and Vascular Anesthesia
Issue number1
StatePublished - Feb 2012


  • aminocaproic acid
  • antifibrinolytics
  • apixaban
  • blood conservation guidelines
  • blood salvage
  • cardiopulmonary bypass
  • clopidogrel
  • coronary artery bypass surgery
  • dabigatran
  • direct thrombin inhibitor
  • erythropoietin
  • factor Xa inhibitor
  • factor concentrates
  • femoral artery
  • fresh frozen plasma
  • heart failure
  • leukoreduction
  • microplegia
  • minimally invasive surgery
  • percutaneous coronary intervention
  • platelet blockade
  • point-of-care testing
  • radial artery
  • rivaroxaban
  • thoracic endovascular repair
  • tranexamic acid
  • transcatheter aortic valve implantation
  • transcatheter mitral valve repair
  • ultrafiltration

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Anesthesiology and Pain Medicine


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