TY - JOUR
T1 - The Sixth Annual Symposium of the Midwest Aging Consortium
AU - Sturmlechner, Ines
AU - Ashiqueali, Sarah A.
AU - Martini, Hélène
AU - Valdivieso, Karla
AU - Franco, Ana Catarina
AU - Guthikonda, Prashanth
AU - Dosch, Andrew J.
AU - Prieto, Luis I.
AU - Asmussen, Niels C.
AU - Latham, Amanda S.
AU - Redden, James T.
AU - Leitschuh, Ethan A.
AU - Mashek, Douglas G.
AU - Passos, João F.
AU - Rodriguez-Lopez, Jhonny
AU - Monroe, T. Blake
AU - Bernlohr, David A.
AU - Robbins, Paul D.
AU - Knopf, Bailey A.
AU - Lamming, Dudley W.
AU - Johnston, Matthew J.
AU - Brown-Borg, Holly M.
AU - Tye, Spencer A.
AU - Rhoads, Timothy W.
AU - Gate, David M.
AU - Childs, Bennett G.
AU - Baker, Darren J.
AU - Li, Xinna
AU - Jang, In Hwa
AU - Camell, Christina D.
AU - Miller, Zachary
AU - Phatnani, Hemali
AU - Konopka, Adam R.
AU - Haak, Andrew J.
AU - Vanegas-Avendano, Natalia
AU - Akula, Ramya N.
AU - Limkar, Ajinkya R.
AU - Ricke, William A.
AU - Leiser, Scott F.
AU - Correia, Jacinta
AU - Bai, Hua
AU - Olszewski, Szczepan
AU - Seldeen, Kenneth L.
AU - Budinger, G. R.Scott
AU - Morales-Nebreda, Luisa C.
AU - Winter, Deborah R.
AU - McCrady-Spitzer, Shelly K.
AU - Anderson, Rozalyn M.
AU - Mihaylova, Maria M.
AU - Rojas, Mauricio
AU - Mora, Ana L.
AU - LeBrasseur, Nathan K.
AU - Schafer, Marissa J.
N1 - Publisher Copyright:
© The Author(s) 2025.
PY - 2026/3/1
Y1 - 2026/3/1
N2 - Geroscience research benefits from interdisciplinary approaches, team science, and collaborations, which collectively facilitate the discovery of aging mechanisms and their translation into tangible, clinical interventions. Since its inception in 2019, the Midwest Aging Consortium (MAC) has provided an engaging platform for aging researchers in the United States’ Midwest to connect, collaborate, and exchange ideas. The Sixth Annual Research Symposium of the MAC held at the Mayo Clinic in Rochester, Minnesota, in April 2025 highlighted the continued impact of the MAC in bringing together aging researchers, including many trainees and early career investigators, into a collaborative environment. This record-setting event featured interdisciplinary research on key aging mechanisms, including lipid metabolism, mitochondrial dysfunction, stress response, cellular senescence, and immune adaptations across organ systems. New therapeutic concepts and clinical trial approaches were presented. Cutting-edge methodologies including single-cell and spatial transcriptomics, metabolomics, and organoid cultures, to dissect aging process in tissue-specific and systemic contexts also were presented. Overall, the MAC symposium underscored the translational potential of geroscience and reinforced the MAC’s mission to accelerate aging research through regional collaborations and innovation.
AB - Geroscience research benefits from interdisciplinary approaches, team science, and collaborations, which collectively facilitate the discovery of aging mechanisms and their translation into tangible, clinical interventions. Since its inception in 2019, the Midwest Aging Consortium (MAC) has provided an engaging platform for aging researchers in the United States’ Midwest to connect, collaborate, and exchange ideas. The Sixth Annual Research Symposium of the MAC held at the Mayo Clinic in Rochester, Minnesota, in April 2025 highlighted the continued impact of the MAC in bringing together aging researchers, including many trainees and early career investigators, into a collaborative environment. This record-setting event featured interdisciplinary research on key aging mechanisms, including lipid metabolism, mitochondrial dysfunction, stress response, cellular senescence, and immune adaptations across organ systems. New therapeutic concepts and clinical trial approaches were presented. Cutting-edge methodologies including single-cell and spatial transcriptomics, metabolomics, and organoid cultures, to dissect aging process in tissue-specific and systemic contexts also were presented. Overall, the MAC symposium underscored the translational potential of geroscience and reinforced the MAC’s mission to accelerate aging research through regional collaborations and innovation.
KW - Geroscience Conference
KW - Midwest Aging Consortium
UR - https://www.scopus.com/pages/publications/105029658027
UR - https://www.scopus.com/pages/publications/105029658027#tab=citedBy
U2 - 10.1093/gerona/glaf280
DO - 10.1093/gerona/glaf280
M3 - Article
C2 - 41429578
AN - SCOPUS:105029658027
SN - 1079-5006
VL - 81
JO - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
JF - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
IS - 3
M1 - glaf280
ER -