The Role of Angioplasty Alone in Intracranial Atherosclerosis: 2-Dimensional Operative Video

Salomon Cohen-Cohen, Giuseppe Lanzino, Waleed Brinjikji

Research output: Contribution to journalComment/debatepeer-review


Intracranial atherosclerosis disease (IAD) is the cause of stroke in up to 10% of cases. Symptomatic IAD results mainly from hypoperfusion, embolic phenomenon, and occlusion. Treatment consists of conservative management with aggressive medical treatment, surgery, and endovascular therapy.1,2 This video is about a 62-yr-old male who presented with left-sided hemiparesis and right gaze preference secondary to an acute ischemic stroke in the right middle cerebral artery (MCA) territory treated initially with  tissue plasminogen activator (tPA). Head computed tomography (CT) angiography (CTA) revealed occlusion of the extracranial and cavernous segments of the internal carotid artery (ICA). CT perfusion (CTP) showed hypoperfusion in the MCA territory and magnetic resonance imaging (MRI) revealed multifocal, wedge-shaped areas of restricted diffusion in the right hemisphere. During his hospitalization, he experienced worsening of his symptoms in the setting of hypoperfusion (hypotension). The patient underwent a cerebral angiogram with thrombectomy and submaximal angioplasty (SA). Successful revascularization of the right ICA was obtained. No procedure-related complications occurred, and the patient's neurological exam improved. SA can be as efficient and a safer option than conventional angioplasty or angioplasty and stenting for symptomatic IAD. The patient consented for the procedure and for the video production.

Original languageEnglish (US)
Pages (from-to)E350-E351
JournalOperative Neurosurgery
Issue number5
StatePublished - May 1 2021


  • Intracranial atherosclerosis disease
  • Revascularization
  • Submaximal angioplasty

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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