The neoplastic appendix: A practical approach

Dora Lam-Himlin, Elizabeth A. Montgomery

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Neoplastic processes in the appendix are histologically similar to their colonic counterparts, and recognition of these neoplasms is relatively straightforward. However, reporting and tumour staging of the neoplastic appendix can be complex, given numerous proposed classification systems, the uncertainty surrounding extra-appendiceal spread, and the frequently low-grade histology. Prognostication and clinical decisions regarding treatment rely heavily upon the completeness of the pathology report. This review discusses the clinicopathologic features of the epithelial neoplasms of the appendix, including colonic-type (non-mucinous) adenomas and adenocarcinomas, mucinous neoplasms, classical carcinoid tumours (well-differentiated neuroendocrine tumours), and goblet cell carcinoids with a focus on prognosis, terminology and pertinent points to include in the pathology report.

Original languageEnglish (US)
Pages (from-to)395-403
Number of pages9
JournalDiagnostic Histopathology
Issue number9
StatePublished - Sep 2011


  • Adenocarcinoma ex goblet cell carcinoid
  • Appendiceal neoplasms
  • Appendix
  • Carcinoid
  • Cystadenoma
  • Goblet cell carcinoid
  • Pseudomyxoma peritonei

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology


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