Cerebral glgantism, or Sotos’ disease, is a rare disorder of unknown cause characterized by the early onset of excessive growth, acromegallc features, and some degree of mental retardation. Although several endocrinologic abnormalities have been described in such patients, none has been specific or sufficient to explain the clinical features. Our report of the endocrinologic and pathologic aspects in a young woman with Sotos’ disease includes the first microanatomic study of the hypothalamus and Immunocytochemical examination of the pituitary gland in this disorder.
|Original language||English (US)|
|Number of pages||4|
|Journal||American Journal of Diseases of Children|
|State||Published - Jul 1985|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health