The Global Burden of Aortic Stenosis

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110 Scopus citations


Degenerative, calcific valvular aortic stenosis (AS), caused by an active process of atherosclerosis, calcification and ossification, is the most common cause of AS in industrialized nations. The prevalence of calcific AS is age-dependent, and thus is expected to increase due to demographic aging of the global population. It is well recognized that severe AS carries a poor prognosis if left untreated. Despite this recognition, many patients are inappropriately denied surgery because of perceived risk. This article will examine the etiology, prevalence, and current trends in the treatment of degenerative AS focusing on indications for surgical aortic valve replacement.

Original languageEnglish (US)
Pages (from-to)565-571
Number of pages7
JournalProgress in Cardiovascular Diseases
Issue number6
StatePublished - May 2014


  • Aortic stenosis
  • Aortic valve replacement
  • Prevalence

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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