The erythrocyte-immune complex-glomerulonephritis connection in man

L. A. Hebert, F. G. Cosio

Research output: Contribution to journalEditorialpeer-review

69 Scopus citations


Over the past five years there has been a groundswell of evidence from numerous laboratories indicating that the erythrocytes of humans and other primates may play a key role in the handling of immune complexes (IC) in the circulation. Most of this work has been reported outside the traditional nephrology literature and, to date, there has been no comprehensive review of this rapidly expanding subject from the nephrology perspective. However, there have been two excellent reviews stressing the basic immunology aspects of this topic. It is the goal of this review to examine the experimental evidence suggesting an important role for erythrocyte/IC interactions in the primate and to discuss their potential clinical implications.

Original languageEnglish (US)
Pages (from-to)877-885
Number of pages9
JournalKidney international
Issue number4
StatePublished - 1987

ASJC Scopus subject areas

  • Nephrology


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