The effects of antidepressants on sleep: A review

J. T. Gursky, L. E. Krahn

Research output: Contribution to journalReview articlepeer-review

60 Scopus citations


Sleep disturbances are a frequent complication of depressive disorders and their treatment. Familiarity with the interaction among sleep, depression, and antidepressant medications may assist the clinician in selecting agents to suit the needs of individual patients. The authors review the current knowledge of changes in sleep architecture associated with particular antidepressant agents and with depressive illness, as well as the theoretical relevance of such changes to the antidepressant effect. Articles for review were found through a Medline search on the terms "polysomnography," "sleep," "antidepressants," and "insomnia" in English-language papers published from 1966 through March 2000. Additional articles were found in the reference lists of relevant papers.

Original languageEnglish (US)
Pages (from-to)298-306
Number of pages9
JournalHarvard Review of Psychiatry
Issue number6
StatePublished - Dec 1 2000

ASJC Scopus subject areas

  • Psychiatry and Mental health


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