The effect of paired stimuli on blink reflex latencies in normal subjects

Devon I. Rubin, Elliot L. Dimberg, Kathleen D. Kennelly

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Introduction: In this study we assessed the effect of paired stimuli on the latencies and amplitudes of the blink reflex. Methods: Blink reflexes were performed with single and paired (5-ms interstimulus interval) stimuli in 47 patients. The changes in latencies between paired and single stimuli were calculated. Results: Paired stimulation produced two types of R1 waveform morphologies: single- and double-peaked waveforms. Increases in R1 and contralateral R2 latencies with paired stimulation were significantly higher in those with singlepeaked R1 responses compared to those with double-peaked R1 responses. Conclusions: Interpreting the blink reflex latencies using paired stimulation requires visualization of the R1 waveform morphology. A double-peaked R1 response requires no change in normal latency values, but the latency of a singlepeaked R1 should be interpreted from the second shock artifact. The effect on the R2 latency is variable

Original languageEnglish (US)
Pages (from-to)235-240
Number of pages6
JournalMuscle and Nerve
Issue number2
StatePublished - Aug 2011


  • Blink reflex
  • Cranial nerve
  • Late responses
  • Latencies
  • Paired stimulation
  • References

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)


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