The amblyopia treatment index

Stephen R. Cole, Roy W. Beck, Pamela S. Moke, Marianne P. Celano, Carolyn D. Drews, Michael X. Repka, Jonathan M. Holmes, Eileen E. Birch, Raymond T. Kraker, Kevin E. Kip

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


Objective: To develop a questionnaire to assess the acceptability of amblyopia treatment and its effect on the child and family. Methods: A 20-item parental survey was developed and pilot tested on 64 subjects, aged 3 to 6 years, participating in the Amblyopia Treatment Study, a randomized trial comparing patching and atropine as treatments for moderate amblyopia. The survey was administered after 4 weeks of treatment. A descriptive item analysis and an internal consistency reliability analysis were performed. Results: Nineteen of the 20 items demonstrated adequate variability as evidenced by the frequency distributions for item responses. Only 4 (<1%) of 1280 possible item responses were missing, one each by 4 different respondents. Factor analysis identified 3 treatment-related factors - "adverse effects," "compliance," and "social stigma" - among 11 of the 20 items. The internal-consistency reliability α for the 5-item adverse effects subscale was 0.82, the 4-item compliance subscale α was 0.81, and the 2-item social stigma subscale α was 0.84. Conclusions: The Amblyopia Treatment Index appears to be a useful instrument for assessing the impact of amblyopia treatment in 3-to 6-year-old children.

Original languageEnglish (US)
Pages (from-to)250-254
Number of pages5
JournalJournal of AAPOS
Issue number4
StatePublished - Aug 2001

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Ophthalmology


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