The 5q- syndrome: A scientific and clinical update

Ayalew Tefferi, Paul Mathew, Pierre Noël

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


The 5q- syndrome is a subset of the myelodysplastic syndromes characterized by hypolob-ulated micromegakaryocytic hyperplasia and an interstitial deletion of the long arm of chromosome 5. In this concise review, we discuss the current understanding in regard to the genetic basis of the disorder and provide an updated clinical report on 43 patients with the disease who were seen at our institution.

Original languageEnglish (US)
Pages (from-to)375-378
Number of pages4
JournalLeukemia and Lymphoma
Issue number5-6
StatePublished - 1994


  • 5q-
  • Clinical course
  • Molecular genetics
  • Myelodysplastic syndrome

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research


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