Techniques for intraoperative radiation therapy for early-stage breast carcinoma

Daniel M. Trifiletti, Ryan Jones, Shayna L. Showalter, Bruce B. Libby, David R. Brenin, Anneke Schroen, Monica M. Morris, Kelli A. Reardon, Timothy N. Showalter

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Intraoperative radiation therapy (IORT) is a method of accelerated partial breast irradiation developed to replace other longer courses of radiotherapy with a single radiation session administered at the time of breast-conserving surgery. The purpose of this review is to summarize the advantages and disadvantages of breast IORT techniques that are currently available, as well to consider potential alternative techniques for breast IORT or ultra-short course breast radiotherapy. Furthermore, we highlight the published outcomes for the IORT treatment approaches including: electron therapy, superficial photon therapy and other techniques. Potential future directions of IORT are explored including novel IORT techniques utilizing intraoperative brachytherapy with in-room imaging and rapid treatment planning.

Original languageEnglish (US)
Pages (from-to)1047-1058
Number of pages12
JournalFuture Oncology
Issue number7
StatePublished - Apr 1 2015


  • APBI
  • IORT
  • brachytherapy
  • breast
  • intraoperative
  • summary

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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