Targeting the hypoxia pathway to treat pancreatic cancer

Lori A. Erickson, W. Edward Highsmith, Peiwen Fei, Jun Zhang

Research output: Contribution to journalComment/debatepeer-review

20 Scopus citations


The correlation between hypoxia and pancreatic cancer has long been discussed. Hao’s research team made many efforts on revealing the oncogenic function of hypoxic inducible factor-1 (HIF-1) in pancreatic cancer progression and development in recent years. Based on their research, they linked micro-environmental regulation of pancreatic cancer and its clinical significance. Hao’s research team suggests it is a promising approach to target HIF-1 for the management of pancreatic cancer progression and invasion.

Original languageEnglish (US)
Pages (from-to)2029-2031
Number of pages3
JournalDrug Design, Development and Therapy
StatePublished - Apr 8 2015


  • HIF-1
  • Hypoxia
  • Pancreatic cancer

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery


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