Tako-Tsubo cardiomyopathy following colonoscopy: Insights on pathogenesis

Misbahuddin Mohammad, Atul K. Patel, Avanti Koirala, Samuel J. Asirvatham

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


We report a case of Tako-Tsubo cardiomyopathy (TTC) occurring after colonoscopy. A 60-year-old post menopausal female with syncope following an acute abdominal syndrome underwent diagnostic colonoscopy. Anginal chest pain with marked ST segment elevation occurred the day following the procedure. Coronary angiogram was entirely normal, but left ventriculography showed marked reduction in systolic function along with mid ventricular and apical akinesis. The patient's symptoms completely improved with eventual normalization of ventricular function. The occurrence in this patient of initial vagal syndrome followed by sympathetic stimulation preceding TTC is compared to prior reports with similar provocateurs and implications for pathogenesis discussed.

Original languageEnglish (US)
Pages (from-to)e46-e49
JournalInternational Journal of Cardiology
Issue number3
StatePublished - Mar 17 2011


  • Apical ballooning syndrome
  • Colonoscopy: Chest pain
  • EKG changes
  • Pathogenesis
  • Stress cardiomyopathy
  • Tako-Tsubo cardiomyopathy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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