Systematic review of technical variations for mohs micrographic surgery for melanoma

Aimee E. Krausz, H. William Higgins, Jeremy Etzkorn, Joseph Sobanko, Thuzar Shin, Cerrene Giordano, Stacy L. McMurray, Nicholas Golda, Ian A. Maher, Justin J. Leitenberger, Anna Bar, Rajiv I. Nijhawan, Divya Srivastava, Jerry D. Brewer, Christian L. Baum, Todd E. Holmes, Glenn D. Goldman, Jeremy Bordeaux, Bryan Carroll, Kelly MacarthurChristopher J. Miller

Research output: Contribution to journalReview articlepeer-review


BACKGROUND Mohs micrographic surgery (MMS) for cutaneous melanoma is becoming more prevalent, but surgical technique varies. OBJECTIVE To define variations in published techniques for MMS for melanoma. METHODS AND MATERIALS A systematic review was performed of PubMed, EMBASE, and Scopus databases to identify all articles describing surgical techniques for MMS for melanoma. Technical details were recorded for the preoperative, intraoperative, and postoperative phases of MMS. RESULTS Twenty-four articles were included. Mohs surgeons vary in how they assess clinical margins, how wide a margin they excise on the first MMS layer, and how they process tissue to determine tumor stage and margin clearance during MMS for melanoma. CONCLUSION Mohs micrographic surgery for melanoma is performed with varied surgical techniques. To establish best practices, additional research is necessary to determine how different techniques affect outcomes.

Original languageEnglish (US)
Pages (from-to)1539-1544
Number of pages6
JournalDermatologic Surgery
Issue number12
StatePublished - Dec 1 2021

ASJC Scopus subject areas

  • Surgery
  • Dermatology


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