TY - JOUR
T1 - Sudden Cardiac Death
T2 - Epidemiology, Circadian Variation, and Triggers
AU - Mahmoud, Karim D.
AU - de Smet, Bart J.G.L.
AU - Zijlstra, Felix
AU - Rihal, Charanjit S.
AU - Holmes, David R.
N1 - Funding Information:
Grant sponsors (to KDM): Netherlands Heart Foundation (The Hague, the Netherlands), Groningen University Fund (Groningen, the Netherlands), Marco Polo Fund (Groningen, the Netherlands), Jan Kornelis de Kock Foundation (Groningen, the Netherlands).
PY - 2011/2
Y1 - 2011/2
N2 - Sudden cardiac death (SCD) remains a major health issue accounting for over 5% of annual mortality in the Western world. There are several causes of SCD, most commonly, coronary artery disease. Although identifying the prodrome of SCD has attracted considerable interest, a large proportion of patients die before any medical contact is established. SCD onset seems to follow a circadian pattern, most likely because of exposure to endogenous and exogenous triggers. The aim of the present report is to review the current knowledge of epidemiology, patterns of onset, and triggers of SCD and present directions for future research with a focus on coronary artery disease.
AB - Sudden cardiac death (SCD) remains a major health issue accounting for over 5% of annual mortality in the Western world. There are several causes of SCD, most commonly, coronary artery disease. Although identifying the prodrome of SCD has attracted considerable interest, a large proportion of patients die before any medical contact is established. SCD onset seems to follow a circadian pattern, most likely because of exposure to endogenous and exogenous triggers. The aim of the present report is to review the current knowledge of epidemiology, patterns of onset, and triggers of SCD and present directions for future research with a focus on coronary artery disease.
UR - http://www.scopus.com/inward/record.url?scp=79952018473&partnerID=8YFLogxK
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U2 - 10.1016/j.cpcardiol.2011.01.002
DO - 10.1016/j.cpcardiol.2011.01.002
M3 - Article
C2 - 21356429
AN - SCOPUS:79952018473
SN - 0146-2806
VL - 36
SP - 56
EP - 80
JO - Current Problems in Cardiology
JF - Current Problems in Cardiology
IS - 2
ER -