Sterols in asthma

Mireia Guerau-de-Arellano, Rodney D. Britt

Research output: Contribution to journalReview articlepeer-review


While sterols regulate immune processes key to the pathogenesis of asthma, inhibition of sterols with statin drugs has shown conflicting results in human asthma. Here, a novel understanding of the impact of sterols on type 17 immune responses and asthma lead us to hypothesize that sterols and statins may be relevant to severe asthma endotypes with neutrophil infiltration.

Original languageEnglish (US)
JournalTrends in Immunology
StatePublished - Oct 2022


  • Th17
  • asthma
  • neutrophilic
  • severe
  • statin
  • sterol

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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