Spontaneous Coronary Artery Dissection

Marysia S. Tweet, Rajiv Gulati, Sharonne N. Hayes

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations


Spontaneous coronary artery dissection is an important etiology of nonatherosclerotic acute coronary syndrome, myocardial infarction, and sudden death. Innovations in the catheterization laboratory including optical coherence tomography and intravascular ultrasound have enhanced the ability to visualize intimal disruption and intramural hematoma associated with SCAD. Formerly considered “rare,” these technological advances and heightened awareness suggest that SCAD is more prevalent than prior estimates. SCAD is associated with female sex, young age, extreme emotional stress, or extreme exertion, pregnancy, and fibromuscular dysplasia. The clinical characteristics and management strategies of SCAD patients are different than for atherosclerotic heart disease and deserve specific consideration. This review will highlight recent discoveries about SCAD as well as describe current efforts to elucidate remaining gaps in knowledge.

Original languageEnglish (US)
Article number60
JournalCurrent cardiology reports
Issue number7
StatePublished - Jul 1 2016


  • Acute coronary syndrome
  • Fibromuscular dysplasia
  • Myocardial infarction
  • Pregnancy
  • Spontaneous coronary artery dissection
  • Women

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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