Spiral CT colonography (virtual colonoscopy): Multiobserver study of different image display techniques compared to colonoscopy

Elizabeth G. McFarland, James A. Brink, Jay P. Heiken, Dennis M. Balfe, Daniel A. Hirselj, Thomas K. Pilgram, Vincent Argiro, Benjamin Littenberg

Research output: Contribution to journalConference articlepeer-review

3 Scopus citations


Spiral CT colonography (virtual colonoscopy) is a rapidly developing field with both 2D and 3D display techniques currently used for visualization of colorectal polyps. Our purpose was to perform a multiobserver reader study in a test set of 30 colonic segments to determine the diagnostic performance of 2D MPR, 3D thick slab MPR, and 3D PVR, using colonoscopy as the standard of reference. In this study, CT colonography was performed in a cohort of patients with known polyps immediately prior to colonoscopy, following using a standard bowel prep and air-insufflation. A test set of 30 colonic segments was created, with a total of 22 lesions present, with all findings verified by colonoscopy. Three image displays were tested in this study: 2D multiplanar reformation (MPR), 3D thick slab MPR following 2D MPR review, and 3D perspective volume rendered (PVR) displays following 2D MPR review. Readers independently analyzed each test case in a controlled setting and scored their confidence on a 5 point scale of each focal finding observed. Our results demonstrated high sensitivity for detection of colorectal polyps using 2D MPR in this library of 30 colonic segments. Reader analysis with 3D PVR demonstrated improved characterization of focal findings in selected cases.

Original languageEnglish (US)
Pages (from-to)106-108
Number of pages3
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - Jan 1 1999
EventProceedings of the 1999 Medical Imaging - Physiology and Function from Multidimensional Images - San Diego, CA, USA
Duration: Feb 21 1999Feb 23 1999

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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