Spatial misregistration of vascular flow during MR imaging of the CNS: Cause and clinical significance

T. C. Larson, W. M. Kelly, R. L. Ehman, F. W. Wehrli

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Spatial misregistration of signal recovered from flowing spins within vascular structures is a common phenomenon seen in MR imaging of the CNS. The condition is displayed as a bright line or dot offset from the true anatomic location of the lumen of the imaged vessel. Its origin is the time delay between application of the phase- and frequency-encoding gradients used to locate spins within the plane of section. The principal condition necessary for the production of spatial misregistration is flow oblique to the axis of the phase-encoding gradient. Flow-related enhancement (entry slice phenomenon), even-echo rephasing, and gradient-moment nulling contribute to the production of the bright signal of spatial misregistration. Familiarity with the typical appearance of flow-dependent spatial misregistration permits confirmation of a vessel's patency; identification of the direction of flow; estimation of the velocity of flow; and differentiation of this flow artifact from atheromas, dissection, intraluminal clot, and artifacts such as chemical shift.

Original languageEnglish (US)
Pages (from-to)1041-1048
Number of pages8
JournalAmerican Journal of Neuroradiology
Issue number5
StatePublished - 1990

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology


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