Serious Pulmonary Toxicity Secondary to Novel Hepatitis C Antiviral Therapy in a Liver Transplant Recipient

Richard A. Helmers; Thomas J. Byrne; Lewis J. Wesselius; Kevin O. Leslie

doi:10.1016/j.mayocp.2015.06.015

Serious Pulmonary Toxicity Secondary to Novel Hepatitis C Antiviral Therapy in a Liver Transplant Recipient

Richard A. Helmers, Thomas J. Byrne, Lewis J. Wesselius, Kevin O. Leslie

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Historically, the treatment of hepatitis C virus infection has been difficult, but therapeutic options have improved markedly recently because of the development of novel antiviral therapies. These therapies have been well tolerated. We describe a patient who was receiving such therapy and had development of temporally related and histologically confirmed severe pulmonary toxicity. Pulmonary toxicity should be considered a potential serious complication of novel antiviral therapy for hepatitis C virus infection.

Original language	English (US)
Pages (from-to)	1294-1297
Number of pages	4
Journal	Mayo Clinic proceedings
Volume	90
Issue number	9
DOIs	https://doi.org/10.1016/j.mayocp.2015.06.015
State	Published - Sep 1 2015

ASJC Scopus subject areas

Medicine(all)

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10.1016/j.mayocp.2015.06.015

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title = "Serious Pulmonary Toxicity Secondary to Novel Hepatitis C Antiviral Therapy in a Liver Transplant Recipient",

abstract = "Historically, the treatment of hepatitis C virus infection has been difficult, but therapeutic options have improved markedly recently because of the development of novel antiviral therapies. These therapies have been well tolerated. We describe a patient who was receiving such therapy and had development of temporally related and histologically confirmed severe pulmonary toxicity. Pulmonary toxicity should be considered a potential serious complication of novel antiviral therapy for hepatitis C virus infection.",

author = "Helmers, {Richard A.} and Byrne, {Thomas J.} and Wesselius, {Lewis J.} and Leslie, {Kevin O.}",

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AU - Helmers, Richard A.

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AU - Leslie, Kevin O.

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N2 - Historically, the treatment of hepatitis C virus infection has been difficult, but therapeutic options have improved markedly recently because of the development of novel antiviral therapies. These therapies have been well tolerated. We describe a patient who was receiving such therapy and had development of temporally related and histologically confirmed severe pulmonary toxicity. Pulmonary toxicity should be considered a potential serious complication of novel antiviral therapy for hepatitis C virus infection.

AB - Historically, the treatment of hepatitis C virus infection has been difficult, but therapeutic options have improved markedly recently because of the development of novel antiviral therapies. These therapies have been well tolerated. We describe a patient who was receiving such therapy and had development of temporally related and histologically confirmed severe pulmonary toxicity. Pulmonary toxicity should be considered a potential serious complication of novel antiviral therapy for hepatitis C virus infection.

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Serious Pulmonary Toxicity Secondary to Novel Hepatitis C Antiviral Therapy in a Liver Transplant Recipient

Abstract

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