Rosai-Dorfman disease presenting as multiple soft tissue masses

Phillip M. Young, Mark J. Kransdorf, H. Thomas Temple, Fatemeh Mousavi, Philip G. Robinson

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


Rosai-Dorfman disease is a rare clinical disorder which may present in many forms. While classically a disease of lymph nodes, soft tissue involvement is fairly common. Soft tissue involvement can occur without any lymphatic or systemic involvement, and may be difficult to diagnose. We describe a patient presenting with multiple soft tissue masses which on biopsy proved to be isolated cutaneous Rosai-Dorfman disease. MR imaging showed two well-defined nonspecific superficial masses that enhanced intensely. Review of the literature suggests that when this disease presents in soft tissue, multiple foci of involvement may be common. Although rare, Rosai-Dorfman disease should be considered in the differential diagnosis of patients presenting with multiple soft tissue masses.

Original languageEnglish (US)
Pages (from-to)665-669
Number of pages5
JournalSkeletal Radiology
Issue number10
StatePublished - Oct 2005


  • Imaging
  • MRI
  • Radiology
  • Rosai-Dorfman
  • Sinus histiocytosis
  • Soft tissue

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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