Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulation

Erika Driver-Dunckley; Virgilio Gerald H. Evidenter; Charles H. Adler; Renee Hillman; Jose Hernandez; Geoffrey Fletcher; Mark K. Lyons

doi:10.1002/mds.20911

Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulation

Erika Driver-Dunckley, Virgilio Gerald H. Evidenter, Charles H. Adler, Renee Hillman, Jose Hernandez, Geoffrey Fletcher, Mark K. Lyons

Neurology

Research output: Contribution to journal › Article › peer-review

68 Scopus citations

Abstract

We report on 6 advanced Parkinson's disease (PD) patients who underwent bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery whose restless legs syndrome (RLS) improved postoperatively. Despite a mean 56% decrease in their levodopa equivalents postoperatively, their RLS scores dropped by a mean of 84% (100% in three). Our findings suggest that bilateral STN DBS surgery can improve RLS in patients with advanced PD.

Original language	English (US)
Pages (from-to)	1287-1289
Number of pages	3
Journal	Movement Disorders
Volume	21
Issue number	8
DOIs	https://doi.org/10.1002/mds.20911
State	Published - Aug 2006

Keywords

Deep brain stimulation surgery
Parkinson's disease
Restless legs syndrome

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1002/mds.20911

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title = "Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulation",

abstract = "We report on 6 advanced Parkinson's disease (PD) patients who underwent bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery whose restless legs syndrome (RLS) improved postoperatively. Despite a mean 56% decrease in their levodopa equivalents postoperatively, their RLS scores dropped by a mean of 84% (100% in three). Our findings suggest that bilateral STN DBS surgery can improve RLS in patients with advanced PD.",

keywords = "Deep brain stimulation surgery, Parkinson's disease, Restless legs syndrome",

author = "Erika Driver-Dunckley and Evidenter, {Virgilio Gerald H.} and Adler, {Charles H.} and Renee Hillman and Jose Hernandez and Geoffrey Fletcher and Lyons, {Mark K.}",

year = "2006",

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AU - Driver-Dunckley, Erika

AU - Evidenter, Virgilio Gerald H.

AU - Adler, Charles H.

AU - Hillman, Renee

AU - Hernandez, Jose

AU - Fletcher, Geoffrey

AU - Lyons, Mark K.

PY - 2006/8

Y1 - 2006/8

N2 - We report on 6 advanced Parkinson's disease (PD) patients who underwent bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery whose restless legs syndrome (RLS) improved postoperatively. Despite a mean 56% decrease in their levodopa equivalents postoperatively, their RLS scores dropped by a mean of 84% (100% in three). Our findings suggest that bilateral STN DBS surgery can improve RLS in patients with advanced PD.

AB - We report on 6 advanced Parkinson's disease (PD) patients who underwent bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) surgery whose restless legs syndrome (RLS) improved postoperatively. Despite a mean 56% decrease in their levodopa equivalents postoperatively, their RLS scores dropped by a mean of 84% (100% in three). Our findings suggest that bilateral STN DBS surgery can improve RLS in patients with advanced PD.

KW - Deep brain stimulation surgery

KW - Parkinson's disease

KW - Restless legs syndrome

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Restless legs syndrome in Parkinson's disease patients may improve with subthalamic stimulation

Abstract

Keywords

ASJC Scopus subject areas

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