Recommendations of the National Heart, Lung, and Blood Institute working group on cerebrovascular biology and disease

Costantino Iadecola, Stephen S. Goldman, David R. Harder, Donald D. Heistad, Zvonimir S. Katusic, Michael A. Moskowitz, J. Marc Simard, Michael A. Sloan, Richard J. Traystman, Paul A. Velletri

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


The National Heart, Lung, and Blood Institute (NHLBI) convened a conference call working group, consisting of experts in stroke and cerebrovascular biology on January 28, 2005. The purpose of this working group was to develop a prioritized set of recommendations for NHLBI to establish a focused and comprehensive set of research activities in cerebrovascular biology and disease. Three thematic areas of research emerged: (1) molecular and cellular neurobiology of cerebral blood vessels, focusing on genomics and proteomics, neurovascular signaling and cerebrovascular embryogenesis, development and plasticity; (2) resource development, involving the development of new methodological approaches for normal and altered function of the neurovascular unit, collaborative research, and training in cerebrovascular pathobiology; and (3) cerebrovascular diseases and translational approaches, addressing vascular mechanisms of disease, the role of risk factors, importance of biomarkers with the ultimate goal of developing new treatments.

Original languageEnglish (US)
Pages (from-to)1578-1581
Number of pages4
Issue number6
StatePublished - Jun 2006


  • Cerebrovascular disease
  • Microcirculation

ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing


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