@article{8bd86e5576dc4d2f90f1c0466dc53fdc,
title = "Rate of infection following revision anterior cruciate ligament reconstruction and associated patient- and surgeon-dependent risk factors: Retrospective results from MOON and MARS data collected from 2002 to 2011",
abstract = "Infection is a rare occurrence after revision anterior cruciate ligament reconstruction (rACLR). Because of the low rates of infection, it has been difficult to identify risk factors for infection in this patient population. The purpose of this study was to report the rate of infection following rACLR and assess whether infection is associated with patient- and surgeon-dependent risk factors. We reviewed two large prospective cohorts to identify patients with postoperative infections following rACLR. Age, sex, body mass index (BMI), smoking status, history of diabetes, and graft choice were recorded for each patient. The association of these factors with postoperative infection following rACLR was assessed. There were 1423 rACLR cases in the combined cohort, with 9 (0.6%) reporting postoperative infections. Allografts had a higher risk of infection than autografts (odds ratio, 6.8; 95% CI, 0.9–54.5; p =.045). Diabetes (odds ratio, 28.6; 95% CI, 5.5–149.9; p =.004) was a risk factor for infection. Patient age, sex, BMI, and smoking status were not associated with risk of infection after rACLR.",
keywords = "allograft, autograft, diabetes, revision ACL reconstruction",
author = "{MARS Group} and Brophy, {Robert H.} and Wright, {Rick W.} and Huston, {Laura J.} and Haas, {Amanda K.} and Allen, {Christina R.} and Anderson, {Allen F.} and Cooper, {Daniel E.} and DeBerardino, {Thomas M.} and Dunn, {Warren R.} and Lantz, {Brett (Brick) A.} and Barton Mann and Spindler, {Kurt P.} and Stuart, {Michael J.} and Albright, {John P.} and Annunziato Amendola and Andrish, {Jack T.} and Annunziata, {Christopher C.} and Arciero, {Robert A.} and Bach, {Bernard R.} and Baker, {Champ L.} and Bartolozzi, {Arthur R.} and Baumgarten, {Keith M.} and Bechler, {Jeffery R.} and Berg, {Jeffrey H.} and Bernas, {Geoffrey A.} and Brockmeier, {Stephen F.} and Bush-Joseph, {Charles A.} and Butler, {Jay Brad V.} and Campbell, {John D.} and Carey, {James L.} and Carpenter, {James E.} and Cole, {Brian J.} and Cooper, {Jonathan M.} and Cox, {Charles L.} and {Alexander Creighton}, Robert and Dahm, {Diane L.} and David, {Tal S.} and Flanigan, {David C.} and Frederick, {Robert W.} and Ganley, {Theodore J.} and Garofoli, {Elizabeth A.} and Gatt, {Charles J.} and Gecha, {Steven R.} and Giffin, {James Robert} and Hame, {Sharon L.} and Hannafin, {Jo A.} and Harner, {Christopher D.} and Harris, {Norman Lindsay} and Hechtman, {Keith S.} and Levy, {Bruce A.}",
note = "Funding Information: This study received funding from the AOSSM, Smith & Nephew, National Football League Charities, and Musculoskeletal Transplant Foundation. This project was partially funded by grant No. 5R01‐AR060846 and grant No. R01‐AR053684 from the National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases. We would also like to thank Jack T. Andrish, MD (Cleveland Clinic, Cleveland, OH USA) and John D. Campbell, MD (Bridger Orthopedic and Sports Medicine, Bozeman, MT USA) for their effort and leadership on this project. After many years of dedication to the advancement of orthopedics, both are enjoying a well‐deserved and happy retirement. Funding Information: This study received funding from the AOSSM, Smith & Nephew, National Football League Charities, and Musculoskeletal Transplant Foundation. This project was partially funded by grant No. 5R01-AR060846 and grant No. R01-AR053684 from the National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases. We would also like to thank Jack T. Andrish, MD (Cleveland Clinic, Cleveland, OH USA) and John D. Campbell, MD (Bridger Orthopedic and Sports Medicine, Bozeman, MT USA) for their effort and leadership on this project. After many years of dedication to the advancement of orthopedics, both are enjoying a well-deserved and happy retirement. We wish to thank the research coordinators, analysts and support staff from the Multicenter Orthopaedic Outcomes Network (MOON) sites and Multicenter ACL Revision Study (MARS) sites, whose efforts related to regulatory requirements, data collection, subject follow-up, data quality control, analyses, and manuscript preparation have made this consortium successful. We also thank all the subjects who generously enrolled and participated in this study. Publisher Copyright: {\textcopyright} 2020 Orthopaedic Research Society. Published by Wiley Periodicals LLC",
year = "2021",
month = feb,
doi = "10.1002/jor.24871",
language = "English (US)",
volume = "39",
pages = "274--280",
journal = "Journal of Orthopaedic Research",
issn = "0736-0266",
publisher = "John Wiley and Sons Inc.",
number = "2",
}