Radiotherapy for a rising PSA following radical prostatectomy

O. Kenneth Macdonald, Steven E. Schild

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Controversy exists regarding the management of recurrent disease, heralded by a rising prostate specific antigen (PSA), in men who have undergone primary treatment of prostate cancer by radical prostatectomy. Although retrospective in nature, the use of salvage radiation therapy (RT) after prostatectomy has been extensively investigated and reported. Salvage RT alone is likely not optimal for every man presenting with recurrent disease after RP. Those with palpable recurrent disease or unfavorable disease characteristics are less likely to benefit from salvage RT alone and may respond better to a combined modality approach. However, early referral and proper patient selection maximizes the potential for durable biochemical control after salvage RT in men with rising PSA alone.

Original languageEnglish (US)
Pages (from-to)57-61
Number of pages5
JournalUrologic Oncology: Seminars and Original Investigations
Issue number1
StatePublished - Jan 2004


  • Prostate cancer
  • Prostate specific antigen
  • Prostatectomy
  • Salvage radiation therapy

ASJC Scopus subject areas

  • Oncology
  • Urology


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