Pyrrole-based partial peptidic mimic of neurotensin (8-13): Design and synthesis

Javid H. Zaidi; Fazal Naeem; Nida Ambreen; Khalid M. Khan; Yuan Ping Pang; Bernadette Cusack; Elliot Richelson; Awais Anwar; Wolfgang Voelter

doi:10.2174/157017806774964530

Pyrrole-based partial peptidic mimic of neurotensin (8-13): Design and synthesis

Javid H. Zaidi, Fazal Naeem, Nida Ambreen, Khalid M. Khan, Yuan Ping Pang, Bernadette Cusack, Elliot Richelson, Awais Anwar, Wolfgang Voelter

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The synthesis of pyrrole-based semipeptidic mimic of neuropeptide neurotensin (8-13) [NT(8-13)] is described. The design of this NT mimic is based on substitution of indole by a pyrrole nucleus.

Original language	English (US)
Pages (from-to)	21-24
Number of pages	4
Journal	Letters in Organic Chemistry
Volume	3
Issue number	1
DOIs	https://doi.org/10.2174/157017806774964530
State	Published - Jan 2006

Keywords

Drug design
Neurotensin
Partial peptidic mimic
Synthesis

ASJC Scopus subject areas

Biochemistry
Organic Chemistry

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10.2174/157017806774964530

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abstract = "The synthesis of pyrrole-based semipeptidic mimic of neuropeptide neurotensin (8-13) [NT(8-13)] is described. The design of this NT mimic is based on substitution of indole by a pyrrole nucleus.",

keywords = "Drug design, Neurotensin, Partial peptidic mimic, Synthesis",

author = "Zaidi, {Javid H.} and Fazal Naeem and Nida Ambreen and Khan, {Khalid M.} and Pang, {Yuan Ping} and Bernadette Cusack and Elliot Richelson and Awais Anwar and Wolfgang Voelter",

year = "2006",

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AU - Zaidi, Javid H.

AU - Naeem, Fazal

AU - Ambreen, Nida

AU - Khan, Khalid M.

AU - Pang, Yuan Ping

AU - Cusack, Bernadette

AU - Richelson, Elliot

AU - Anwar, Awais

AU - Voelter, Wolfgang

PY - 2006/1

Y1 - 2006/1

N2 - The synthesis of pyrrole-based semipeptidic mimic of neuropeptide neurotensin (8-13) [NT(8-13)] is described. The design of this NT mimic is based on substitution of indole by a pyrrole nucleus.

AB - The synthesis of pyrrole-based semipeptidic mimic of neuropeptide neurotensin (8-13) [NT(8-13)] is described. The design of this NT mimic is based on substitution of indole by a pyrrole nucleus.

KW - Drug design

KW - Neurotensin

KW - Partial peptidic mimic

KW - Synthesis

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Pyrrole-based partial peptidic mimic of neurotensin (8-13): Design and synthesis

Abstract

Keywords

ASJC Scopus subject areas

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