Pulmonary Artery Angiomatoid Fibrous Histiocytoma Mimicking a Large Pulmonary Embolism

Logan P. Haug, Matthew A. Zarka, Jonathan D'Cunha, Francis X. Downey, Mahesh Seetharam, Ming Yang

Research output: Contribution to journalReview articlepeer-review


A 39-year-old man presented with progressive dyspnea and lower extremity edema. Doppler ultrasound demonstrated bilateral leg partially occluded venous thromboses. A V/Q scan revealed a mismatched perfusion defect involving the entire right middle and lower lobes. Subsequent CT pulmonary angiogram revealed a mass lesion occluding the right interlobar pulmonary artery. Endobronchial ultrasound-guided fine-needle aspiration of the mass was concerning for neoplasm. 18F-FDG PET/CT demonstrated marked hypermetabolism of the mass lesion. Patient underwent transmediastinal right pneumonectomy with histopathologic diagnosis of pulmonary artery angiomatoid fibrous histiocytoma, a rare etiology mimicking large pulmonary artery embolism.

Original languageEnglish (US)
Pages (from-to)E738-E739
JournalClinical nuclear medicine
Issue number12
StatePublished - Dec 1 2022


  • V/Q scan
  • angiomatoid fibrous histiocytoma
  • pulmonary artery

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Pulmonary Artery Angiomatoid Fibrous Histiocytoma Mimicking a Large Pulmonary Embolism'. Together they form a unique fingerprint.

Cite this