Protons vs Photons for Brain and Skull Base Tumors

Safia K. Ahmed; Paul D. Brown; Robert L. Foote

doi:10.1016/j.semradonc.2017.11.001

Protons vs Photons for Brain and Skull Base Tumors

Safia K. Ahmed, Paul D. Brown, Robert L. Foote

Radiation Oncology

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

The physical characteristics of proton therapy result in steeper dose gradients and superior dose conformality compared to photon therapy. These properties render proton therapy ideal for skull base tumors requiring dose escalation for optimal tumor control, and may also be beneficial for brain tumors as a means of mitigating radiation-related adverse effects. This review summarizes the literature regarding the role of proton therapy compared to photon therapy in the treatment of adult brain and skull base tumors.

Original language	English (US)
Pages (from-to)	97-107
Number of pages	11
Journal	Seminars in Radiation Oncology
Volume	28
Issue number	2
DOIs	https://doi.org/10.1016/j.semradonc.2017.11.001
State	Published - Apr 2018

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

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10.1016/j.semradonc.2017.11.001

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title = "Protons vs Photons for Brain and Skull Base Tumors",

abstract = "The physical characteristics of proton therapy result in steeper dose gradients and superior dose conformality compared to photon therapy. These properties render proton therapy ideal for skull base tumors requiring dose escalation for optimal tumor control, and may also be beneficial for brain tumors as a means of mitigating radiation-related adverse effects. This review summarizes the literature regarding the role of proton therapy compared to photon therapy in the treatment of adult brain and skull base tumors.",

author = "Ahmed, {Safia K.} and Brown, {Paul D.} and Foote, {Robert L.}",

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year = "2018",

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AU - Brown, Paul D.

AU - Foote, Robert L.

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N2 - The physical characteristics of proton therapy result in steeper dose gradients and superior dose conformality compared to photon therapy. These properties render proton therapy ideal for skull base tumors requiring dose escalation for optimal tumor control, and may also be beneficial for brain tumors as a means of mitigating radiation-related adverse effects. This review summarizes the literature regarding the role of proton therapy compared to photon therapy in the treatment of adult brain and skull base tumors.

AB - The physical characteristics of proton therapy result in steeper dose gradients and superior dose conformality compared to photon therapy. These properties render proton therapy ideal for skull base tumors requiring dose escalation for optimal tumor control, and may also be beneficial for brain tumors as a means of mitigating radiation-related adverse effects. This review summarizes the literature regarding the role of proton therapy compared to photon therapy in the treatment of adult brain and skull base tumors.

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Protons vs Photons for Brain and Skull Base Tumors

Abstract

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