Proteomics of human pancreatic juice

Mads Gronborg; Anirban Maitra; Akhilesh Pandey

doi:10.1007/978-1-59745-432-2_17

Proteomics of human pancreatic juice

Mads Gronborg, Anirban Maitra, Akhilesh Pandey

Laboratory Medicine and Pathology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Pancreatic juice has recently been characterized in detail using proteomic methods. The cataloging of proteins from healthy individuals and those diagnosed with pancreatic cancer has revealed the presence of a number of proteins in pancreatic juice that could serve as potential biomarkers for cancer. Because obtaining pancreatic juice is not trivial, it is possible that these biomarkers can be detected in serum using more sensitive methods like ELISA. Here, we discuss the protein constituents of pancreatic juice with special reference to cancer biomarkers.

Original language	English (US)
Title of host publication	Proteomics of Human Body Fluids
Subtitle of host publication	Principles, Methods, and Applications
Publisher	Humana Press Inc.
Pages	377-397
Number of pages	21
ISBN (Electronic)	9781597454322
ISBN (Print)	9781588296573
DOIs	https://doi.org/10.1007/978-1-59745-432-2_17
State	Published - 2007

Keywords

LC-MS/MS
Pancreatic juice
biomarker discovery
mass spectrometry
quantitative proteomics

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1007/978-1-59745-432-2_17

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AU - Maitra, Anirban

AU - Pandey, Akhilesh

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AB - Pancreatic juice has recently been characterized in detail using proteomic methods. The cataloging of proteins from healthy individuals and those diagnosed with pancreatic cancer has revealed the presence of a number of proteins in pancreatic juice that could serve as potential biomarkers for cancer. Because obtaining pancreatic juice is not trivial, it is possible that these biomarkers can be detected in serum using more sensitive methods like ELISA. Here, we discuss the protein constituents of pancreatic juice with special reference to cancer biomarkers.

KW - LC-MS/MS

KW - Pancreatic juice

KW - biomarker discovery

KW - mass spectrometry

KW - quantitative proteomics

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BT - Proteomics of Human Body Fluids

PB - Humana Press Inc.

ER -

Proteomics of human pancreatic juice

Abstract

Keywords

ASJC Scopus subject areas

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