Prosthetic joint infection

Aaron J. Tande, Robin Patel

Research output: Contribution to journalArticlepeer-review

620 Scopus citations


Prosthetic joint infection (PJI) is a tremendous burden for individual patients as well as the global health care industry. While a small minority of joint arthroplasties will become infected, appropriate recognition and management are critical to preserve or restore adequate function and prevent excess morbidity. In this review,wedescribe the reported risk factors for and clinical manifestations of PJI.Wediscuss the pathogenesis of PJI and the numerous microorganisms that can cause this devastating infection. The recently proposed consensus definitions of PJI and approaches to accurate diagnosis are reviewed in detail. An overview of the treatment and prevention of this challenging condition is provided.

Original languageEnglish (US)
Pages (from-to)302-345
Number of pages44
JournalClinical Microbiology Reviews
Issue number2
StatePublished - Apr 2014

ASJC Scopus subject areas

  • Epidemiology
  • General Immunology and Microbiology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Infectious Diseases


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