Prominent subpleural fat with chronic pleural disease

Thomas Hartman

Research output: Chapter in Book/Report/Conference proceedingChapter


Imaging In the setting of a focal or diffuse pleural abnormality, the underlying subpleural fat can be thickened (Figures 67.1–67.3). This is likely due to hypertrophy secondary to chronic inflammation. As such, the presence of thickening of the subpleural fat is a strong indicator of chronic and, therefore, benign pleural disease (1–4). However, it should be stressed that thickened subpleural fat is not seen with every case of benign pleural disease and therefore the absence of thickening of the subpleural fat is not indicative of malignancy. Importance Recognition of thickened subpleural fat adjacent to a pleural abnormality is a strong predictor that the associated pleural abnormality is benign.

Original languageEnglish (US)
Title of host publicationPearls and Pitfalls in Thoracic Imaging
Subtitle of host publicationVariants and Other Difficult Diagnoses
PublisherCambridge University Press
Number of pages2
ISBN (Electronic)9780511977701
ISBN (Print)9780521119078
StatePublished - Jan 1 2011

ASJC Scopus subject areas

  • Medicine(all)


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