Progranulin gene mutation with an unusual clinical and neuropathologic presentation

Keyphrases

• Neuropathology 100%
• Gene mutation 100%
• Progranulin mutation 100%
• Frontotemporal Dementia 40%
• Ubiquitin 40%
• Family Members 40%
• Neuronal Loss 40%
• Dementia Diseases 40%
• Intranuclear Inclusions 40%
• Glial Cytoplasmic Inclusion 40%
• Alzheimer's Disease 20%
• Autopsy 20%
• Temporal Lobe 20%
• Parkinsonism 20%
• TAR DNA-binding Protein 43 (TDP-43) 20%
• Immunohistochemistry 20%
• Frontal Cortex 20%
• Positive Inclusion 20%
• Frontotemporal Lobar Degeneration 20%
• Neurite 20%
• Gliosis 20%
• Genetic Studies 20%
• Striatal 20%
• Striatum 20%
• Cortex 20%
• Atrophy 20%
• Temporal Cortex 20%
• Dysarthria 20%
• Atypical Presentation 20%
• Oculomotor Abnormalities 20%
• Buccolingual 20%

Neuroscience

• Gene Mutation 100%
• Progranulin 100%
• Temporal Lobe 40%
• Ubiquitin 40%
• Alzheimer's Disease 20%
• Parkinsonism 20%
• Frontotemporal Dementia 20%
• Frontal Lobe 20%
• Immunohistochemistry 20%
• Neurite 20%
• Gliosis 20%
• Striatum 20%
• Dysarthria 20%
• Frontal Variant Frontotemporal Dementia 20%