Primary tetralogy of Fallot repair: Predictors of intensive care unit morbidity

Alexander C. Egbe, Santosh C. Uppu, Alexander J.C. Mittnacht, Umesh Joashi, Deborah Ho, Khanh Nguyen, Shubhika Srivastava

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Background: Primary repair of tetralogy of Fallot has low surgical mortality, but some patients still experience significant postoperative morbidity. Our objectives were to review our institutional experience with primary tetralogy of Fallot repair, and identify predictors of intensive care unit morbidity. Methods:We reviewed all patients with tetralogy of Fallot who underwent primary repair in infancy from 2001 to 2012. Preoperative, operative, and postoperative demographic and morphologic data were analyzed. Intensive care unit morbidity was defined as prolonged intensive care unit stay (≥7 days) and/or prolonged duration of mechanical ventilation (≥48 h). Results: 97 patients who underwent primary surgical repair during the study period were included in the study. The median age was 4.9 months (range 1-9 months) and the median weight was 5.3 kg (range 3.1-9.8 kg). There was no early surgical mortality. The incidence of junctional ectopic tachycardia and persistent complete heart block was 2% and 1%, respectively. The median intensive care unit stay was 6 days (range 2-21 days) and the median duration of mechanical ventilation was 19 h (range 0-136 h). Age and weight were independent predictors of intensive care unit stay, while surgical era predicted the duration of mechanical ventilation. Conclusion: Primary tetralogy of Fallot repair is a safe procedure with low mortality and morbidity in a medium-sized program with outcomes comparable to national standards. Age and weight at the time of surgery were significant predictors of morbidity.

Original languageEnglish (US)
Pages (from-to)794-799
Number of pages6
JournalAsian Cardiovascular and Thoracic Annals
Issue number7
StatePublished - Sep 2014


  • Infant
  • artificial
  • postoperative complications
  • respiration
  • risk factors
  • tetralogy of Fallot

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine


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