Personalized assessment and management of women at risk for breast cancer in North America

Sandhya Pruthi, Ruth Heisey, Therese Bevers

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Many women at increased risk for breast cancer would benefit from referral for genetic testing, enhanced screening, preventive therapy or risk-reducing surgery. We present a visual model and a step-wise approach to assist with a personalized risk stratification and management of these women. We present current recommendations with respect to lifestyle behaviors and mammographic screening, and we review the current evidence regarding enhanced screening and risk-reducing therapies. We discuss the usefulness of three risk-assessment tools in determining whether a woman qualifies for genetic testing, enhanced screening or preventive therapy and present four cases to demonstrate the usefulness of this approach in the clinical setting.

Original languageEnglish (US)
Pages (from-to)213-224
Number of pages12
JournalWomen's Health
Issue number2
StatePublished - Mar 1 2015


  • breast cancer
  • genetic testing
  • intensive screening
  • preventive therapy
  • risk assessment
  • risk calculators
  • risk-reducing surgery

ASJC Scopus subject areas

  • General Medicine


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