Perioperative Management of Patients with Glioblastoma

Gaetano De Biase, Diogo P. Garcia, Angela Bohnen, Alfredo Quiñones-Hinojosa

Research output: Contribution to journalReview articlepeer-review


The clinical presentation of glioblastomas is varied, and definitive diagnosis requires pathologic examination and study of the tissue. Management of glioblastomas includes surgery and adjuvant chemotherapy and radiotherapy, with surgery playing an important role in the prognosis of these patients. Awake craniotomy plays a crucial role in tumors in or adjacent to eloquent areas, allowing surgeons to maximize resection, while minimizing iatrogenic deficits. However, the prognosis remains dismal. This article presents the perioperative management of patients with glioblastoma including tools and surgical adjuncts to maximize extent of resection and minimize poor outcomes.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalNeurosurgery clinics of North America
Issue number1
StatePublished - Jan 2021


  • Awake brain surgery
  • Glioblastoma
  • Temozolamide

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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