TY - JOUR
T1 - Percutaneous Image-Guided Thermal Ablation of Adrenal Metastasis from Melanoma
T2 - A Single-Institution Experience
AU - Jang, Samuel
AU - Eiken, Patrick W.
AU - Atwell, Thomas D.
AU - Markovic, Svetomir N.
AU - Bancos, Irina
AU - Welch, Brian T.
N1 - Publisher Copyright:
© 2021 SIR
PY - 2021/9
Y1 - 2021/9
N2 - The outcomes of technically successful image-guided percutaneous thermal ablation of melanoma adrenal metastases involving 11 tumors in 9 consecutive patients over 12 years (2009–2020) were evaluated. All patients had multiple treated metastatic sites, and 44.4% (4/9) had greater than 5 metastatic sites. The mean maximal tumor diameter was 3.6 ± 1.6 cm. The local recurrence-free survival at 1 year was 85.7%. With a median survival of 19.4 months, 66.6% (6/9) of patients died from tumor progression. The 1- and 3-year overall survival rate was 60.0% and 30.0%, respectively. All patients were pretreated with alpha-adrenergic blockade, and 36% (4/11) developed a hypertensive crisis. The median hospital length of stay was 1 day (range, 1–2 days), without any major complications. Thermal ablation of adrenal metastasis from a melanoma provides acceptable local control and a good safety profile.
AB - The outcomes of technically successful image-guided percutaneous thermal ablation of melanoma adrenal metastases involving 11 tumors in 9 consecutive patients over 12 years (2009–2020) were evaluated. All patients had multiple treated metastatic sites, and 44.4% (4/9) had greater than 5 metastatic sites. The mean maximal tumor diameter was 3.6 ± 1.6 cm. The local recurrence-free survival at 1 year was 85.7%. With a median survival of 19.4 months, 66.6% (6/9) of patients died from tumor progression. The 1- and 3-year overall survival rate was 60.0% and 30.0%, respectively. All patients were pretreated with alpha-adrenergic blockade, and 36% (4/11) developed a hypertensive crisis. The median hospital length of stay was 1 day (range, 1–2 days), without any major complications. Thermal ablation of adrenal metastasis from a melanoma provides acceptable local control and a good safety profile.
KW - Thermal ablation, adrenal metastasis, melanoma
UR - http://www.scopus.com/inward/record.url?scp=85114058144&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85114058144&partnerID=8YFLogxK
U2 - 10.1016/j.jvir.2021.06.002
DO - 10.1016/j.jvir.2021.06.002
M3 - Article
C2 - 34144185
AN - SCOPUS:85114058144
SN - 1051-0443
VL - 32
SP - 1288
EP - 1291
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
IS - 9
ER -