Percutaneous cryoablation of anterior renal masses: Technique, efficacy, and safety

Grant D. Schmit, Thomas D. Atwell, Bradley C. Leibovich, Matthew R. Callstrom, Anil N. Kurup, David A. Woodrum, J. William Charboneau

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


OBJECTIVE. The safety and efficacy of renal tumor ablation are related, in part, to tumor location. Anterior tumors present a challenge due to the risk of injury to adjacent structures. The purpose of this study was to review the techniques, complications, and short-term outcomes of percutaneous cryoablation of anterior renal masses at a single institution. MATERIALS AND METHODS. We retrospectively identified the cases of 35 patients with 38 anterior renal masses managed with percutaneous imaging-guided cryoablation of renal tumors from March 2003 through February 2009. The technical success of the ablation procedure, serious complications, and evidence of local tumor recurrence were evaluated for each patient. RESULTS. The average maximal diameter of the anterior renal masses was 2.9 cm (SD, 0.9 cm; range, 1.4-4.8 cm). A single cryoablation procedure was performed for treatment of each patient, and technically successful ablation was achieved for all 38 tumors. A single severe adverse event occurred in one of the 35 patients (3% major complication rate). This patient had a pulmonary embolism (diagnosed at CT angiography the day after ablation). He recovered and was discharged from the hospital with anticoagulant medication only 2 days after the procedure. No local tumor recurrence was identified in any of the 29 patients who underwent follow-up contrast-enhanced CT or MRI with images available for review 3 months or longer from the time of ablation (mean, 18 months; range, 3-45 months). CONCLUSION. Percutaneous cryoablation of anterior renal masses can be performed with high technical success and low complication rates. The lack of local renal tumor recurrence at short-term follow-up evaluation in this study is encouraging, but long-term follow-up is necessary to ensure the durability of treatment.

Original languageEnglish (US)
Pages (from-to)1418-1422
Number of pages5
JournalAmerican Journal of Roentgenology
Issue number6
StatePublished - Dec 1 2010


  • Ablation
  • Cryoablation
  • Kidney

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Percutaneous cryoablation of anterior renal masses: Technique, efficacy, and safety'. Together they form a unique fingerprint.

Cite this