Paraneoplastic and metastatic neurologic complications of Merkel cell carcinoma

Scott D.Z. Eggers, Diva R. Salomao, Robert P. Dinapoli, Steven Vernino

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Merkel cell carcinoma is a rare primary cutaneous neuroendocrine tumor that is locally aggressive and frequently accompanied by distant metastases. Neurologic complications of Merkel cell carcinoma are rare. We describe a 69-year-old man who presented with Lambert-Eaton myasthenic syndrome and was found to have Merkel cell carcinoma. The paraneoplastic syndrome improved with initial treatment of the malignancy. He subsequently developed a solitary brain metastasis and died of leptomeningeal carcinomatosis.

Original languageEnglish (US)
Pages (from-to)327-330
Number of pages4
JournalMayo Clinic proceedings
Issue number3
StatePublished - 2001

ASJC Scopus subject areas

  • General Medicine


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