Optical coherence tomography in gastroenterology: A review and future outlook

Tsung Han Tsai, Cadman L. Leggett, Arvind J. Trindade, Amrita Sethi, Anne Fré Swager, Virendra Joshi, Jacques J. Bergman, Hiroshi Mashimo, Norman S. Nishioka, Eman Namati

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations


Optical coherence tomography (OCT) is an imaging technique optically analogous to ultrasound that can generate depth-resolved images with micrometer-scale resolution. Advances in fiber optics and miniaturized actuation technologies allow OCT imaging of the human body and further expand OCT utilization in applications including but not limited to cardiology and gastroenterology. This review article provides an overview of current OCT development and its clinical utility in the gastrointestinal tract, including disease detection/differentiation and endoscopic therapy guidance, as well as a discussion of its future applications.

Original languageEnglish (US)
Article number121716
JournalJournal of Biomedical Optics
Issue number12
StatePublished - Dec 2017


  • Barrett's esophagus
  • Endoscopic imaging
  • Gastroenterology
  • Inflammatory bowel disease
  • Optical biopsy
  • Optical coherence tomography
  • Volumetric laser endomicroscopy

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering
  • Biomaterials


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