Nonspecific interstitial pneumonia

Jay H. Ryu, Jeffrey L. Myers, David E. Midthun, William W. Douglas

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Nonspecific interstitial pneumonia (NSIP) refers to a histologic pattern of interstitial pneumonia occurring in various clinical contexts. Although relatively nonspecific, this pattern of interstitial pneumonia is distinctive in that it lacks characteristics of usual interstitial pneumonia (UIP). Most patients with biopsy diagnoses of NSIP have clinical features suggestive of idiopathic pulmonary fibrosis (IPF). In this latter context, NSIP is associated with a significantly better prognosis than UIP. Indeed, NSIP likely accounts for many historical reports of 'corticosteroid-responsive IPF' and should be distinguished from UIP.

Original languageEnglish (US)
Pages (from-to)104-108
Number of pages5
JournalClinical Pulmonary Medicine
Issue number2
StatePublished - Mar 1998


  • Idiopathic pulmonary fibrosis
  • Interstitial fibrosis
  • Usual interstitial pneumonia

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine


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